Siemens to Acquire Dotmatics for $5.1B

Siemens has announced a $5.1 billion acquisition of Dotmatics from Insight Partners, with closing expected in the first half of fiscal 2026. Dotmatics provides R&D informatics software for life sciences, combining widely used scientific applications—such as GraphPad Prism, SnapGene, and Geneious—with its AI-native platform that supports multimodal data integration, adaptive workflows, and domain-specific machine learning to assist research in areas like drug discovery, antibody engineering, and materials science.

A central element of Dotmatics’ offering is the Luma Scientific Intelligence Platform, an AI-native system designed for adaptive, multimodal scientific workflows. The platform incorporates:

• Assistive AI to automate routine research tasks and respond to natural language inputs.
• Doman-Specific AI to improve predictive accuracy in tasks such as flow cytometry data analysis.
• Integrated Multimodal AI for simulating complex biological processes across datasets, such as protein efficacy or drug developability.

Luma also supports workflow automation through a low-code/no-code interface, data harmonization, instrument integration, and generative AI tools for querying and visualization. It is cloud-native, built on infrastructure including AWS and Databricks, and offers integrations with over 100 scientific instruments.

Dotmatics’ software portfolio spans multiple domains: bioinformatics (SnapGene, Geneious Prime, Geneious Biologics), cheminformatics (Vortex), data analysis and visualization (GraphPad Prism), electronic lab notebooks (ELN & Data Discovery Platform), flow cytometry (OMIQ, FCS Express), multimodal scientific intelligence (Luma platform), and proteomics (Protein Metrics).

The acquisition supports Siemens’ strategy to expand its industrial software presence into life sciences via its Siemens Xcelerator platform. Siemens estimates the move increases its total addressable software market by $11 billion and claims it will help unify research and manufacturing data across value chains.

Dotmatics is projected to generate over $300 million in revenue in fiscal 2025 with adjusted EBITDA margins above 40%. Siemens expects long-term revenue synergies to exceed $500 million annually.

Dotmatics serves more than 14,000 organizations and over 2 million scientists worldwide. Its software is used in antibody engineering, small molecule discovery, proteomics, and materials science, with a focus on breaking down data silos and enhancing research continuity through AI-driven automation and data integration.

Topics: Startups & Deals