Bristol-Myers Squibb Company, through its subsidiaries, engages in the discovery, development, licensing, manufacturing, marketing, distribution and sale of pharmaceuticals and nutritional products.

The company operates in two segments, Pharmaceuticals and Nutritionals.
- The Nutritionals segment is operated through the company's subsidiary Mead Johnson Nutrition Company (Mead Johnson).
- The Pharmaceuticals segment is made up of the global pharmaceutical and international consumer medicines business.